The description "🔚💔👩‍❤️‍💋‍👨🙅‍♀️👋" related to "It ends with us" could be interpreted as follows: "At the conclusion, hearts break as two people, represented by a couple emoji, realize they must part ways. The woman is depicted with a gesture of refusal, indicating her decision to end the relationship. With a final goodbye, their journey together comes to an end."